Approximately 6 million minor burns worldwide are treated medically each year, usually with anti-microbials and dressings to maintain hydration and protect the wound. Hospital admission is required for approximately 100,000 burns in the US and 10,000 in the UK. These require more advanced and expensive care which may include tissue grafting and other surgical interventions often meaning a prolonged hospital stay.
A recent survey of burns care specialists identified four properties as desirable or essential for an ideal burns dressing: 1. non-adhesion, 2. absorbency, 3. antimicrobial activity, and 4. ease of removal.
As polled directly, most of the respondents were of the opinion that such a dressing was currently not available [Selig et al, 2012].
Our NO-generating dressing system has been designed to be non-adherent over the wound bed, is highly absorbent, is a potent, broad spectrum anti-microbial and is easy to remove.
The most common type of wound; there are approximately 100 million surgical incisions per annum and approximately 50 million traumatic wounds, including lacerations caused by accidental injury. This market segment is well served by commodity products such as sutures, staples and a large variety of dressings.
However, surgical site infection (SSI) is a well recognised problem. In the US in 2012, in over 16 million operative procedures the SSI rate was 1.9% leading to a directly attributable 6,840 deaths.
Although several currently available dressings purport to reduce the risk of SSI, the latest Cochrane review of 2011 stated “No evidence was identified to suggest that any dressing significantly reduced the risk of developing an SSI compared with leaving wounds exposed or compared with alternative dressings in people who had surgical wounds healing by secondary intention”.
A dressing that actively reduces the chance of infection has a real opportunity to make a significant difference to this problem.